Effect of Tobacco Alkaloids on the Endocrine System

Alkaloids in tobacco and cigarette smoke causes malfunction of the endocrine system. Under certain conditions, smoking may be a risk factor for the development of hormone dependent pathology. Researching the relationship between smoking and sex steroid hormone status was based on the investigation of serum androgens and estrogens in men, smokers and nonsmokers. Comparative determinations were made in men without apparent endocrine pathology, on the one hand and, on the other hand, in patients with prostatic pathology characterized by impaired metabolism of sex steroid hormones. The results of this study could contribute to develop effective ways to quit smoking or to relieve the negative effects of smoking on the body.